AI-engineered proteins for immune‑mediated disease

Evozyne designs novel therapeutic proteins with generative AI to solve immunology’s toughest challenges.

Our AI-native platform creates mechanisms that natural evolution never produced and accelerates the path from concept to clinic. We focus on immune-mediated diseases with high unmet need, where current biologics and small molecules fail too many patients.

Why It Matters

Immune diseases continue to rise. Many patients don’t respond to today’s therapies or lose response over time. Evozyne designs and builds proteins with precision, durability, and selectivity that overcome these limitations.

What We Do

Design

EvoGen, our AI-native engine, learns how protein sequences drive function. It designs new proteins optimized for potency, stability, specificity, and immunogenicity.

Build & Test

EvoLab, our high-throughput experimental facility, synthesizes and evaluates thousands of candidates each design cycle generating vast troves of novel, proprietary data.

Translate

We move proteins engineered for therapeutic use into our immunology pipeline, including IgG proteases, next-generation cytokines, and respiratory disease candidates.

Our Impact

Evozyne is one of the few AI-native biotechs creating de novo therapeutic proteins and advancing them toward clinical evaluation. As the system learns, the pipeline expands, creating a scalable path to new immune therapies.

Featured Research

Peer-reviewed publications demonstrate platform performance, including:

  • microPublication Biology: ML-guided design of synthetic proteins with superior thermotolerance.
  • PNAS: ProT-VAE, developed with NVIDIA, achieving major gains in functional activity and stability.