Nearly half of the world's disease burden - from prevention to diagnostics to treatment - could be addressed by synthetic biology in the next 20 years.
Have a protein design problem that can cure diseases?
Enable discovery and development of efficacious therapeutics
- Optimize protein-based therapeutic candidates for improved pharmacokinetics and pharmacodynamics
- Unlock the potential of gene and cell-based therapy through novel gene editing enzymes
- Develop diverse synthetic molecules for addressing “undruggable” targets
Produce sustainable and scalable medicinal chemistry
- Improve reaction efficiencies of biosynthesis of active pharmaceutical ingredients
- Optimize a candidate drug’s bioactivity and bioavailability using engineered enzymes such as halogenases
- Design novel bioorthogonal conjugation protocols as drug delivery vehicles
Promote novel disease detection methods for early clinical intervention
- Create new rapid diagnostics using enzymatic biosensors
- Enable PCR-free infectious and genetic disease detection
- Design enzyme cocktails capable of detecting multiple targets simultaneously